whoami

kevin a. scott

drug discovery computational chemistry chemical biology san francisco, CA

co-founder and director of discovery chemistry at stealth medicines, working at the intersection of computational drug discovery, chemical biology, and AI-driven protein dynamics.

my work focuses on targeting dynamic proteins — cryptic pockets, allosteric sites, and protein-protein interaction interfaces — using covalent chemoproteomic platforms and AI-guided molecular design.

when not in the lab, i'm out in san francisco with kaos and entropie.

kaos and entropie at koret quad
kaos & entropie · koret quad, ucsf

info

position co-founder & director of discovery chemistry, stealth medicines
location san francisco, california
focus covalent chemoproteomic platforms · PTM-targeted drug discovery · AI-guided molecular design
twitter / x @sculpturatus
github github.com/sculpturatus
youtube @sculpturatus

research interests

cysteine reactivity profiling isoTOP-ABPP cryptic pocket discovery allosteric modulation covalent probe design biology AlphaFold + MD pipelines DDD platforms chemical space navigation protein dynamics

tools & platforms

chemical space surveyor

cysteine-reactive covalent probe platform mapping the epiproteome via isoTOP-ABPP mass spectrometry, integrated with AlphaFold → docking → MD computational pipeline.

surveyor chemscape

interactive chemical space visualization tool for drug discovery. PCA, UMAP, and custom descriptor plotting across large molecular datasets.

view project → launch app →